In the sciences, the design process could include experimental design or the design of scientific models. Explain why insulin injections are not the course of treatment for all diabetics. The Insulin Level graph shows that Anna Garcia has Type 1 diabetes, because it indicates that there was no insulin produced and Patient B had Type 2 diabetes, because the insulin level was high and did not drop back to 150. The insulin storage is modeled as a three compartment model with X 1, X 2, and an equation for the dynamics of the provision factor P. Record your ideas in your laboratory journal and discuss these features with a partner. The glucose dependent transition functions u 1,…, u 4 describe provision and redistribution processes according to the target distribution.
This is expected in the physiological case without abnormal exposure to glucose. Imagine that you are a healthcare professional who has the task of explaining the connection between insulin and glucose to a group of adults who are either at risk for diabetes or have just been diagnosed. Biological experiments concerning the cell cycle are often done by flow cytometry. These long carbon chains are hard to break apart and are therefore good for storage. Insulin is the main regulator of glucose uptake in target cells.
The glucose is stored in the liver and muscle as glycogen and stops the body from using fat as a source of energy. Insulin is the strongest agent known, it promotes the storage and synthesis of lipids, protein, and carbohydrates and their breakdown and release into the circulation of the body. Outline the path of the major blood vessels to and from the heart: Activity 4. In Type 1 diabetes, no insulin is produced. An alternative interpretation would be variability of sensitivity on cell level.
Models are a very important tool for explaining complex processes in science, technology, and engineering. There are two types of fatty acids, saturated and unsaturated, both have long carbon chains, but unsaturated fats have one or more double bond in its chain. This chemical communication is highly specific and often involves molecules called proteins. . The other process is an insulin dependent glucose uptake mainly by muscle and fat cells which is influenced by insulin sensitivity p 8 and depends on blood insulin concentration I. Cells open their glucose channels. There are also possibilities to simulate the regulatory system in a type 1 diabetes scenario.
Write notes in your laboratory journal or notebook under a heading for each step. A positive to this method is that it shows both the positive and negative feedbacks in an organized way, but a negative is that is it more like a note sheet. Fatty acids are also used as the structure of the cell membrane, which makes sense because of its strong carbon chain, and cell communication and bone structure. The initial values for this simulation with corresponding units are given in Table and the parameters in Table. The specific protein molecules are referred to as signal molecules because they carry the signal from one cell to another. Secretion of insulin consists of the releasable amount of insulin molecules p 9 X 1 in relation to the blood volume bv.
Therefore, it can be shown that condition 10 holds for all positive values of the variables. This process helps to produce consistency, quality of work, and repeatable procedures for people to share. Glucose G plays an important role in regulating the processes within the insulin secretion model. What are some strategies you can use to assess the credibility of websites and to determine which information is reliable and can be used to help you complete your Biomedical Sciences projects? In fact, some investigators refer to metabolic syndrome as the insulin resistance syndrome. This double bond creates a kink in the chain. But how do you know that what you read is accurate? Nonetheless, insulin resistance can extend to other tissues, notably the liver, causing a generalized derangement of metabolism. If the colors match and the drawings are very specific to what you drew it is a very strong reference.
Recognize that the regulation of blood sugar is necessary to avoid severe and life-threatening diabetic emergencies: Activity 2. Insulin facilitates tissue uptake of glucose in all organs except the brain, which can use glucose without insulin. The protein binds to the second cell because that cell has a receptor for it. The connection between insulin resistance and metabolic syndrome is not fully understood. The latter consists mainly of glucose uptake by the brain and other nervous tissues which is assumed to be constant in our model. Show your summary to your teacher and get approval before moving to Part 2.
This is a typical behavior of insulin release reported in several biological publications e. Make sure that the model accurately depicts the role of the following terms in blood sugar regulation: o Glucose transport proteins o Cell membrane o Glucose o Blood o Cell o Insulin o Insulin receptors To complete this task, follow the steps below. Record all ideas in your laboratory journal. Therefore, insulin injections are not the course of treatment for all diabetics. The different parts of the model will be described in detail in the following section. Our model builds a theoretical basis for description and explanation of dynamics derived from biological experiments.